Reconstitute the content of the vial in 1 mL of water. For western blot analysis of PrPc, dilute to a final concentration of 1 µg/mL and use BSA as blocking reagent. For EIA and flow cytometry, the optimal working must be determined empirically (currently between 0.1 and 1 µg/mL).
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease.
This antibody recognises the C-terminal part of the protein but it was not possible to identify a continuous epitope for this antibody.
Air intake and screw for long time monitoring option.
Previous catalog number: 05027-662-PE103